Comparison of immune responses to zirconia, polyether ether ketone (PEEK), and stainless-steel in orthopaedic implants
Aim Orthopedic implants must meet specific criteria, including mechanical strength, durability, and biocompatibility. This study compares the immune response of zirconia, polyether ether ketone (PEEK), and stainless-steel implants in vivo, focusing on lymphocyte and fibroblast infiltration as indicators of immune activation. Methods A total of 27 ...
By Agung Riyanto Budi Santoso, Respati Suryanto Dradjat, Edi Mustamsir, Setyawan Purnomo Sakti, Panji Sananta, Hidayat Sujuti, Heri Suroto
The effect of liquid nitrogen exposure on the proliferative phase of Achilles tendon healing in Rattus norvegicus rats
Aim Tendon healing involves a crucial proliferative phase, during which fibroblasts and fibrocytes orchestrate collagen deposition. The use of liquid nitrogen (LN) in orthopedic oncology may inadvertently affect adjacent tendon tissues. This study aimed to evaluate the impact of LN exposure on the histological features of tendon healing. Methods T...
By Istan Irmansyah Irsan, Edi Mustamsir, Panji Sananta, Satria Pandu Persada Isma, Dandy Drestanto Adiwignyo, Hudzaifah Al Azmi Manaf, Adytia Andreyta Refa
An animal model in rat for secondary osteoporosis: the effect of gonadotropin-releasing hormone (GnRH) agonists, low calcium diet, and immobilization on tartrate-resistant acid phosphatase 5b (TRACP-5b) and procollagen type 1 N-terminal propeptide (PINP) levels
Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...
By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar
Paley cross union protocol for congenital pseudoarthrosis of the tibia
Aim Congenital pseudarthrosis of the tibia (CPT) is a rare, dysplastic condition causing significant disability in the lower limbs. A treatment aims to achieve long-lasting union, prevent limb length discrepancies, and prevent soft tissue lesions. Traditional surgery often yields satisfactory results, but amputation may be proposed in failed cases....
By Panji Sananta, Hasri Nopianto
Correlation between severity of knee osteoarthritis with gender of patients in Secondary Referral Hospital in Indonesia
Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...
By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih
Correlation between severity of knee osteoarthritis with gender of patients in Secondary Referral Hospital in Indonesia
Aim Knee osteoarthritis is a common osteoarthritis, which limits individual’s activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.8% in men. Based on the WHO, the prevalence of osteoarthritis in the world is still high, with 18% in women ...
By Panji Sananta, Avicenna Rahmanda, Dhelya Widasmara, Eka Noviya Fuzianingsih
TGF-1 biomarker level evaluation on fracture healing in a murine model with a bone defect after stromal vascular fraction application
Aim Bone defect is a challenge even for experienced orthopaedic surgeons and it is a significant cause of morbidity in patients and a source of high economic burden in health care. A severe bone defect is a condition whereby the bone tissue cannot undergo natural healing despite surgical stabilization and requires further surgical intervention. Str...
By Panji Sananta, Respati S Dradjat, Rizqi Daniar Rosandi, Lasa Dhakka Siahaan