Comparison of immune responses to zirconia, polyether ether ketone (PEEK), and stainless-steel in orthopaedic implants
Aim Orthopedic implants must meet specific criteria, including mechanical strength, durability, and biocompatibility. This study compares the immune response of zirconia, polyether ether ketone (PEEK), and stainless-steel implants in vivo, focusing on lymphocyte and fibroblast infiltration as indicators of immune activation. Methods A total of 27 ...
By Agung Riyanto Budi Santoso, Respati Suryanto Dradjat, Edi Mustamsir, Setyawan Purnomo Sakti, Panji Sananta, Hidayat Sujuti, Heri Suroto
An animal model in rat for secondary osteoporosis: the effect of gonadotropin-releasing hormone (GnRH) agonists, low calcium diet, and immobilization on tartrate-resistant acid phosphatase 5b (TRACP-5b) and procollagen type 1 N-terminal propeptide (PINP) levels
Aim Osteoporosis is a global health concern, characterized by reduced bone density, microarchitectural changes, and an increased risk of fractures. The prevalence of osteoporosis is rising, particularly in developing countries. In Indonesia, the incidence of upper femur fractures due to osteoporosis is notably high. As human studies are limited, an...
By Panji Sananta, Respati Suryanto Dradjat, Istan Irmansyah Irsan, Andhika Yudistira, Aditya Rosid Dwi Anwar