Aim Diabetes type 2 (DT2) is a metabolic disease characterized by high blood sugar caused by insulin resistance and/or insufficient insulin production. The pathogenesis of DT2 is complicated by both genetic predisposition and environmental and lifestyle variables. At least 150 genetic variants have been linked to the probability of having DT2. The ...

By Ali Adel Dawood, Zayd Kays Omer, Alyaa Farouk Al-Omari

Aim To determine the normative range of ultrasound dimensions for the liver, spleen and kidneys in healthy children according to gender, age, body measurements, body surface area (BSA), and the influence of ethnicity on organ size.Methods The prospective study included children, ranging from full-term neonates to children aged 15, with normal ultra...

By Nina Мekić, Nermin Salkić, Amela Selimović, Majda Mehmedović, Aida Brčić, Zlatan Mehmedović, Amra Šerak, Dijana Dugonjić

Aim To determine the effect of body mass index (BMI) and waist-hip ratio (WHR) on the concentration of circulating sex hormone-binding globulin (SHBG) throughout the menopausal transition.Methods This cross-sectional study included 150 women divided into three groups: premenopausal (n=50), perimenopausal (n=50), and postmenopausal (n=50). The proce...

By Dženana Softić, Lejla Mešalić, Delila Softić

Aim To investigate the relationship between nutritional status (NS) and diet quality (DQ) with the frequency of acute respiratory infections (ARIs) in children aged 5 to 7 years.Methods Data were obtained through questionnaires. Anthropometric measurement, correlations between body mass index (BMI) and DQ with frequency of ARIs were analysed.Result...

By Melika Melunović, Belma Krdžalić-Zečević, Mirela Lisičić-Konaković, Amela Kulašević, Lejla Kurtalić

Aim To investigate the risk for falls in elderly patients treated in the Primary Health Care Centre Gradiška, Bosnia and Herzegovina.Methods This study included 500 patients aged 65 and older. They were chosen randomly by 10 family physicians. Data collection took place every Wednesday and Friday, between January 2022 and July 2022. The pati...

By Suzana Savić, Larisa Gavran, Verica Petrović, Gordana Tešanović, Olivera Batić-Mujanović, Goran Borjanović

Aim To compare the need for intubation and mechanical ventilation after surfactant delivery between less invasive surfactant administration (LISA)-treated and intuba-tion-surfactant-extubation (IN-SURE)-treated premature infants with respiratory distress syndrome (RDS). Methods Retrospective registry-based cohort study enrolled 36 newborns adm...

By Gianluca Dini, Maria Grazia Santini, Federica Celi, Alberto Verrotti

Aim To determine the existence of damage to thin sensitive fibres (Aδ and C) by quantitative sensory testing (QST) in female patients with carpal tunnel syndrome (CTS), the existence of pain, and a connection with the in-nervation field of the nerve itself.Methods Forty-two consecutive female patients with symptoms of CTS participated in the ...

By Tatjana Bućma, Igor Sladojević

Aim To evaluate the essential role of Moringa-albumin (MA) formulation in the maintenance of complement regulatory proteins through CD55 and CD59 on erythrocyte (TER-119).Methods Strepto-zotocin (145 mg/kg) was used to induce diabetes mice. In diabetes mellitus (DM) model mice were treated with MA formulation for 14 days at a D1 - 500 mg/kg (M) + 6...

By Noviana Dwi Lestari, Sulistyo Mulyo Agustini, Moh Dliyauddin, Wahyu Isnia Adharini, Ruri Vivian Nilamsari, Nashi Widodo, Sri Rahayu, Muhaimin Rifa’i

Aim To evaluate diagnostic reliability of accessible laboratory findings in recognition of acute appendicitis (AA). Methods A retrospective study included children aged 0-15 years with abdominal pain that lasted less than 5 days with at least two of the signs/symptoms - abdominal pain, tenderness of the lower right quadrant of the abdomen, "re...

By Sanimir Suljendić, Almira Ćosićkić, Azra Hadžić-Kečalović, Denis Žigić

Aim Despite advancements in the diagnosis, treatment and monitoring of patients with acute coronary syndrome (ACS), morbidity and mortality following ACS remain high. The aim of this study was to actively seek possible predictors of adverse outcomes after ACS aiming to identify high-risk patients promptly.Methods This retrospective cohort study inv...

By Namik Selimović, Amina Marić, Armin Šljivo, Aladin Altic, Irma Fajić, Lana Lekić, Azra Durak-Nalbantić