Aim The infection of the SARS-CoV-2 virus potentially causes a cytokine storm with elevated IL-6 and IL-1β levels. Statin therapy was common among COVID-19 patients due to their cardiovascular comorbidities. However, the effect of statins on COVID-19 infection is unclear. The aim of this study was to evaluate the impact of statin administratio...

By Andrianto Andrianto, Budi Susetyo Pikir, Rizki Amalia, Teuku Yusriza, Fatimah Alzahra, Maya Qurota A’yun, Michael Jonatan

Aim Triple negative breast cancer cells (TNBC) are the population of breast cancer cells that are responsible for cancer recurrence and apoptosis resistance. Unfortunately, current therapies have limited efficacy to TNBC population due to apoptosis resistance and chemoresistance. Tumour suppressor p53 and survivin are primary targets for TNBC thera...

By Deryne Anggia Paramita, Dedy Hermansyah, Desiree Anggia Paramita, Nur Dina Amalina

Aim Given the impact of vascular comorbidities (VC) on the diagnosis, treatment, and outcome of multiple sclerosis (MS), weexamined the incidence and correlation of VC and risk factors for vascular disease in people with MS (PwMS) compared to the general population, and the impact on the physical disability of patients.Methods Cross-sectional study...

By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović-Kovačević, Majda Nazalević-Bursać, Srđan Mavija, Vlado Đajić

Aim To present the experience from collective data regarding patients with retroperitoneal sarcomas that have been operated in and followed up by the University General Hospital of Patras in Rion, Greece, between 2009 and 2020.Methods A retrospective analysis of adult patients treated at our hospital with a diagnosis of primary retroperitoneal sarc...

By Georgios-Ioannis Verras, Francesk Mulita, Konstantinos Bouchagier, Dimitrios Bousis, Dimitrios Kehagias, Elias Liolis, Ioannis Perdikaris, Dimitrios Filis, Panagiotis Perdikaris, Ioannis Panagiotopoulos, Ioannis Maroulis, Nikolaos Benetatos

Aim To investigate analgesic and side effects of different doses of fentanyl in combination with propofol for colonoscopy.Methods This prospective randomized double-blind study conducted between 2019 and 2020 included 64 patients. Patients were randomized: Group 1 (fentanyl 0.5 μg/kg) and Group 2 (fentanyl 1.0 μg/kg) both in combination with ...

By Mirza Kovačević, Adisa Šabanović Adilović, Nermina Rizvanović, Harun Adilović, Malik Ejubović, Alma Jahić Čampara

Aim To determine the value of IFN (intzerferon)-α in the patients with systemic lupus erythematosus (SLE) and to correlate IFN-αwith values of non-specific biochemical parameters of inflammation (C-reactive protein, leukocytes values, erythrocyte sedimentation rate, albumins and globulins).Methods Research included 55 patients with SLE ...

By Lamija Zečević, Edin Begić, Buena Aziri, Izeta Aganović - Mušinović

Aim To investigate possible differences in serum glucose and sodium and potassium concentrations with respect to age, gender and severity of diabetic ketoacidosis.Methods Medical records from 1 January 2017 to 31 December 2019 were reviewed and patients with the diagnosis of diabeticketoacidosis were selected.Results The study included 52 patients....

By Željka Dragila, Dora Rudić, Klara Ćosić, Tatjana Bačun

Aim To investigate clinical presentation of COVID-19 infection in pregnancy, its course during pregnancy, effects on pregnancyoutcomes for both mothers and newborns as well as the potential for vertical transmission.Methods This retrospective observational study included all identifi ed COVID-19-positive pregnant women admitted to the Cantonal Hosp...

By Jasmin Hodžić, Bedrana Muračević, Hana Štimjanin, Rasim Iriškić, Muamera Husika

Aim To determine a prognostic value of cerebral blood flow parameters for the development of neurological sequelae in term neonates with hypoxic ischaemic encephalopathy (HIE).Methods We reviewed medical records of 47 term neonates with HIE who survived until the age of 12 months of life. According tothe Sarnat and Sarnat clinical score, neonates w...

By Emina Hadžimuratović, Suada Branković, Admir Hadžimuratović, Melika Bukvić

Aim To investigate the relationship between adherence to preventive behaviors and risk of COVID-19 infection.Methods In this case-control study, 491 participants were selected through convenience sampling. First, the samples of the casegroup (COVID-19 patients) were selected, and then the control group was matched with the case group based on age, ...

By Reza Hosseinabadi, Shoorangiz Biranvand, Khatereh Anbari