Aim The COVID-19 pandemic has had a major impact on societies and has required adjustments of health systems and changes in work processes, especially in the light of an aging population with increased morbidity and mortality. The primary health care level has a key role in maintaining access to healthcare and in addressing the largest proportion o...

By Jurica Ferenčina, Vladimira Tomšič

Aim Bone defect is a challenge even for experienced orthopaedic surgeons and it is a significant cause of morbidity in patients and a source of high economic burden in health care. A severe bone defect is a condition whereby the bone tissue cannot undergo natural healing despite surgical stabilization and requires further surgical intervention. Str...

By Panji Sananta, Respati S Dradjat, Rizqi Daniar Rosandi, Lasa Dhakka Siahaan

Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies during the last 20 years have investigated its role in oncology. The purpose of this article was to ...

By Themistoklis Paraskevas, Francesk Mulita, Christos Michailides, Georgios-Ioannis Verras, Elias Liolis, Eleousa Oikonomou, Ioannis Perdikaris, Panagiotis Perdikaris, Konstantinos Bouchagier, Ioannis Panagiotopoulos, Dimitrios-Ioannis Kasartzian, Dimitrios Filis, Levan Tchabashvili, Despoina Spyropoulou, Dimitrios Velissaris

Aim To propose a new prognostic classification system for pelvic injuries based on a new detailed and all-encompassing evaluation of the injury pelvic outcome score and to check the prognostic value of this classification and evaluate its reliability and reproducibility.Methods From January 2017 to June 2020 from 156 pelvic fractures treated at our...

By Luigi Meccariello, Cristina Razzano, Cristina De Dominicis, Juan Antonio Herrera-Molpeceres, Francesco Liuzza, Rocco Erasmo, Guido Rocca, Michele Bisaccia, Enzo Pagliarulo, Pietro Cirfeda, David Gómez Garrido, Giuseppe Pica, Giuseppe Rollo

Aim To investigate the effect of umbilical cord-derived mesenchymal stem cells (UC-MSCs) administration among liverfibrosis experimental rat model via the regulation of angiotensin II type 1 receptor (AT1R) and platelet-derived growth factor-β (PDGF-β) due to their therapeutic potential to replace liver transplantation for advanced liver ...

By Taufik Sungkar, Agung Putra, Dharma Lindarto, Rosita Juwita Sembiring

Aim To characterize methicillin-resistant S. aureus (MRSA) strains phenotypically and genotypically and to determine their clonal affiliation, representation and antibiotic resistance profile.Methods A total of 62 randomly selected MRSA isolates of different clinical samples collected from 2009 to 2017 were phenotypically and genotypically analysed...

By Fatima Numanović, Urška Dermota, Jasmina Smajlović, Sandra Janežič, Nijaz Tihić, Zineta Delibegović, Amela Bećirović, Edina Muratović, Merima Gegić

Aim To investigate the effects of surgical reduction of complex acetabular fractures on spine balance, postural stability and quality of life.Methods Twenty-six patients with acetabular fractures surgically treated by open reduction and internal fixation were divided intotwo groups according to the amount of reduction. Group A consisted of 18 patie...

By Vitaliano F. Muzii, Giuseppe Rollo, Guido Rocca, Rocco Erasmo, Gabriele Falzarano, Francesco Liuzza, Michele Bisaccia, Giuseppe Pica, Raffaele Franzese, Luigi Meccariello

Aim To present haemoglobin and ferritin parameters in donors to highlight the importance of serum ferritin testing for the purpose of evaluating iron depots in order to make recommendations for preserving a population of blood donors.Method A prospective study was conducted on 80 blood donors divided in two groups: group I (regular donors, n =40) a...

By Elma Ćatović-Baralija, Gorana Ahmetović-Karić, Sabaheta Hasić, Nesina Avdagić, Nermina Babić

Aim Vascular pathologies have been already explored for the most of their aspects. It is a group of pathologies with unclear ethology and with an evolution in time not easy to forecast. Treatment guidelines are conflicting. The aim of this study was to describe cases in their most practical and technical aspect, especially in complicated conditions...

By Gianpaolo Santini, Pasquale Quassone, Luca Tarotto, Francesco Arienzo, Giuseppe Sarti

Aim A SARS Coronavirus 2 (COVID-19) pandemic drastically changed the way the health system works. In Croatia, lockdownmeasures to curb virus spread lasted from March to May 2020, and all non-essential medical procedures and patients’ visits have been cancelled. The study aimed to compare patients’ flow and interventions in the surgical ...

By Ana Kvolik Pavić, Vedran Zubčić, Slavica Kvolik