Aim The COVID-19 pandemic has had a major impact on societies and has required adjustments of health systems and changes in work processes, especially in the light of an aging population with increased morbidity and mortality. The primary health care level has a key role in maintaining access to healthcare and in addressing the largest proportion o...

By Jurica Ferenčina, Vladimira Tomšič

Aim To determine a prognostic value of cerebral blood flow parameters for the development of neurological sequelae in term neonates with hypoxic ischaemic encephalopathy (HIE).Methods We reviewed medical records of 47 term neonates with HIE who survived until the age of 12 months of life. According tothe Sarnat and Sarnat clinical score, neonates w...

By Emina Hadžimuratović, Suada Branković, Admir Hadžimuratović, Melika Bukvić

Aim Bone defect is a challenge even for experienced orthopaedic surgeons and it is a significant cause of morbidity in patients and a source of high economic burden in health care. A severe bone defect is a condition whereby the bone tissue cannot undergo natural healing despite surgical stabilization and requires further surgical intervention. Str...

By Panji Sananta, Respati S Dradjat, Rizqi Daniar Rosandi, Lasa Dhakka Siahaan

Aim Several biomarkers are currently used as diagnostic and prognostic tools in patients with cancer. Soluble urokinase plasminogen activator receptor (suPAR) is elevated in acute and chronic inflammatory procedures and several observational studies during the last 20 years have investigated its role in oncology. The purpose of this article was to ...

By Themistoklis Paraskevas, Francesk Mulita, Christos Michailides, Georgios-Ioannis Verras, Elias Liolis, Eleousa Oikonomou, Ioannis Perdikaris, Panagiotis Perdikaris, Konstantinos Bouchagier, Ioannis Panagiotopoulos, Dimitrios-Ioannis Kasartzian, Dimitrios Filis, Levan Tchabashvili, Despoina Spyropoulou, Dimitrios Velissaris

Aim To investigate the effect of umbilical cord-derived mesenchymal stem cells (UC-MSCs) administration among liverfibrosis experimental rat model via the regulation of angiotensin II type 1 receptor (AT1R) and platelet-derived growth factor-β (PDGF-β) due to their therapeutic potential to replace liver transplantation for advanced liver ...

By Taufik Sungkar, Agung Putra, Dharma Lindarto, Rosita Juwita Sembiring

Aim In the scientific literature there are no papers that clarify which method of surgical fixation in transverse metacarpal fractures has the best functional outcomes. The aim of this study was to compare the hand strength obtained using two different methods in the treatment of these fractures.Methods A total of 52 patients who presented a transv...

By Andrea Pasquino, Alessandro Tomarchio, Enio De Cruto, Jacopo Conteduca, Damiano Longo, Valentina Russi, Giuseppe Pica, Luigi Meccariello, Giuseppe Rollo

Aim To establish a correlation between immediate post-surgical weight bearing in extracapsular hip fractures and final functional outcome as well as to study the correlation between immediate post-surgical weight bearing and morbidity and mortality during the first year.Methods Retrospective observational cohort study including 495 consecutive pati...

By Enrique Sanchez-Munoz, Beatriz Lozano-Hernanz, Daniel Vicente Velarde-Garrido, Leticia Alarma-Barcia, Victor Trivino Sanchez-Mayoral, Paula Romera-Olivera, Cristina Lopez Palacios

Aim To investigate the effects of surgical reduction of complex acetabular fractures on spine balance, postural stability and quality of life.Methods Twenty-six patients with acetabular fractures surgically treated by open reduction and internal fixation were divided intotwo groups according to the amount of reduction. Group A consisted of 18 patie...

By Vitaliano F. Muzii, Giuseppe Rollo, Guido Rocca, Rocco Erasmo, Gabriele Falzarano, Francesco Liuzza, Michele Bisaccia, Giuseppe Pica, Raffaele Franzese, Luigi Meccariello

Aim Vascular pathologies have been already explored for the most of their aspects. It is a group of pathologies with unclear ethology and with an evolution in time not easy to forecast. Treatment guidelines are conflicting. The aim of this study was to describe cases in their most practical and technical aspect, especially in complicated conditions...

By Gianpaolo Santini, Pasquale Quassone, Luca Tarotto, Francesco Arienzo, Giuseppe Sarti

Aim A SARS Coronavirus 2 (COVID-19) pandemic drastically changed the way the health system works. In Croatia, lockdownmeasures to curb virus spread lasted from March to May 2020, and all non-essential medical procedures and patients’ visits have been cancelled. The study aimed to compare patients’ flow and interventions in the surgical ...

By Ana Kvolik Pavić, Vedran Zubčić, Slavica Kvolik