Aim To investigate analgesic effect of three different regimens of combination of analgesics administered to patients undergoing laparoscopic cholecystectomy.Methods Patients undergoing laparoscopic cholecystectomy were randomly allocated to one of three groups on admission, depending of a prescribed post-operative analgesic regimen. Patients alloc...

By Francesk Mulita, Georgios Karpetas, Elias Liolis, Michail Vailas, Levan Tchabashvili, Ioannis Maroulis

Aim To assess the impact of semi-refined carrageenan (E407a) on hydrophobic regions of phosphololipid bilayer in cell membranes of leukocytes collected from rats orally administered this food additive and white blood cells incubated with E407a.Methods Fluorescent probes (ortho-hydroxy derivatives of 2,5-diaryl-1,3-oxazole) were used to estimate the...

By Anton Tkachenko, Anatolii Onishchenko, Alexander Roshal, Oksana Nakonechna, Tetyana Chumachenko, Yevgen Posokhov

Aim To explore the effects of a molecular pathway from the application of low-intensity direct current (LIDC) for wound healingthrough the pathway signalling growth factor and initiation of fibroblast activation.Methods This randomized clinical trial included 32 patients with open fracture wounds who came to Hasan Sadikin Hospital inBandung, Indone...

By Yoyos Dias Ismiarto, Kemas Abdul Mutholib Luthfi, Mahyudin Mahyudin, Adriel Benedict

Aim To investigate the effect of intermittent traction therapy (ITT) on pain in patients with chronic low back pain (CLBP).Methods A total of 81 patients with CLBP were included: experimental group received ITT (n=40) and control group receivedconservative physical treatment (n=41) 10 times for two weeks. A visual analogue scale (VAS) was used for ...

By Edina Tanović, Damir Čelik, Đemil Omerović, Vanda Zovko Omeragić, Amila Jaganjac, Hadžan Konjo, Emina Rovčanin, Hana Omerović

Aim To investigate the impact of pre-treatment serum total prostate-specific antigen (PSA) level on prevalence of prostate carcinoma detection in prostate core needle biopsy, and its correlation with established prognostic factors.Methods Prostate needle biopsy samples of 115 patients with available pre-treatment serum total PSA (tPSA) level were a...

By Nina Čamdžić, Suada Kuskunović-Vlahovljak, Mirsad Dorić, Svjetlana Radović, Edina Lazović Salčin, Mirsad Babić

Rotator cuff tears (RCT) are a common problem encountered by orthopaedic surgeons. The incidence of re-tears (up to 94%) following surgical repair of RCTs renders the management of RCTs challenging. This higher re-tear rate has been attributed to the failure of healing at the tendon-bone junction. Biological augmentation methods such as growth fact...

By Erdi Özdemir, Dogac Karaguven, Egemen Turhan, Gazi Huri

Aim To report clinical, functional and radiographic results of oneincision distal biceps tendon repair with Toggle Loc (Zimmer-Biomet, Warsaw, Indiana, USA) at an average 4-year follow-up and to assess posterior interosseous nerve injury complications after reconstruction.Methods We conducted a retrospective review of 58 consecutive distal biceps t...

By Silvio Chiossi, Marco Spoliti, Pasquale Sessa, Valerio Arceri, Attilio Basile, Francesca Romana Rossetti, Riccardo Maria Lanzetti

Aim Thyroid nodules are very common and may be found in more than 50% of the population. Fine-needle aspiration cytology(FNAC) of thyroid nodules is a very useful diagnostic tool with high sensitivity and predictive value for diagnosis. The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) uses six categories for thyroid cytology reportin...

By Francesk Mulita, Fotios Iliopoulos, Christos Tsilivigkos, Levan Tchabashvili, Elias Liolis, Charalampos Kaplanis, Ioannis Perdikaris, Ioannis Maroulis

Aim To evaluate if the sinus tarsi approach treated with open reduction and internal fixation (ORIF), without using plate fixation, provided good functional results in active adult population. The hypothesis was that the sinus tarsi approach with limited incision provided good results comparable to other approaches. Methods A total of 78 patients (...

By Paolo Ceccarini, Francesco Manfreda, Rosario Petruccelli, Giuseppe Talesa, Giuseppe Rinonapoli, Auro Caraffa

Aim To evaluate the pattern of indications and a spectrum of colonic pathology, and to determine appropriateness of indications for colonoscopy in order to improve patient selection for colonoscopy.Methods This retrospective study includes 294 patients who were referred to the Gastroenterology Department from a primary carephysician in order to app...

By Nerma Čustović, Lejla Džananović, Ismar Rašić, Nadža Zubčević, Lejla Šaranović-Čečo, Jasmina Redžepagić