Rheumatic heart disease (RHD) is influenced by genetic factor, microorganism's virulence, and environmental factor. The aim of this study was to determine human leukocyte (HLA)-DRB1 allele among children with RHD in Medan, Indonesia. Methods An observational study was conducted at the Department of Child Health, Haji Adam Malik Hospital Medan from ...

By Tina Christina Lumban Tobing, Teddy Ontoseno, Sri Endah Rahayuningsih, Ratna Akbari Ganie, Yahwardiah Siregar

Aim Acute rhinosinusitis (AR) is of viral aetiology and only 0.5-2% develop into acute bacterial rhinosinusitis. Herbal therapy is a promising alternative in acute bacterial rhinosinusitis treatment. The aim of this study was to evaluate the effect of ethanol extract of Poguntano leaves (EEPL) to procalcitonin level and the amount of bacteria in ac...

By Andrina Yunita Murni Rambe, Delfitri Munir, Rosita Juwita Sembiring, Syafruddin Ilyas

Aim To examine the prevalence of undiagnosed depression among primary care elderly patients in the entity of the Republic of Srpska (Bosnia and Herzegovina) as well as the sociodemographic and clinical risk factors associated with depression. Methods A cross-sectional study was conducted between April and June 2019 in nine towns of the Republic of ...

By Kosana Stanetić, Verica Petrović, Bojan Stanetić, Vesna Kević, Mirko Stanetić, Jelena Matović, Srebrenka Kusmuk, Maja Račić

Aim To investigate risk factors for the development of prosthetic joint infection.Methods A group of 50 patients with periprosthetic infection was compared with a group of 100 randomly selected patients with total hip or knee arthroplasty without infectious complications. Twelve risk factors in both groups were analysed. Results Five factors showed...

By Jozef Breznicky, Marian Hlavac, Martin Novak, Matej Hrncar

Aim To evaluate the incidence, modalities of treatment and outcome in paediatric patients with traumatic brain injury (TBI). Methods A retrospective cross-sectional study including 353 paediatric patients with head injury was carried out in the Department of Neurosurgery of University Clinical Centre Sarajevo during the period 1 July 2006-30 June 2...

By Ibrahim Omerhodžić, Nevena Mahmutbegović, Bekir Rovčanin

AimTo determine differences in quantitative traits of digital dermatoglyphics between breast cancer women and the women in the control group (healthy women). Methods This case-control study included digital dermatoglyphics of 50 patients with confirmed breast cancer diagnosis compared with 50 healthy examinees with the absence of familial history o...

By Jasmin Mušanović, Azra Metović, Faruk Husremović, Samir Bejić, Aldina Hasković, Aida Babić, Senad Šljuka

Aim To present diagnostic and therapeutic possibilities for genital and peritoneal tuberculosis, mimicking to other pathological conditions, mainly, ovarian cancer. Methods Transabdominal and transvaginal ultrasound, computerized tomography, Ca125 and HE 4, ROMA-index (Risk of Ovarian Maligancy Algorithm index) and diagnostic laparoscopy were perfo...

By Alexandra Wagner, Ruža Arsenić, Matthias David, Jalid Sehouli, Domagoj Vidosavljević, Irena Rohr

Aim To compare the prevalence of premature rupture of membranes (PROM) and preterm premature rupture of membranes (PPROM) between adolescent and adult pregnancies, and the influence of gestational age and adolescent pregnancy on the frequency of occurrence of PROM and PPROM. Methods This prospective study included 300 pregnant patients, 13 to 35 ye...

By Sergije Marković, Gordana Bogdanović, Anis Cerovac

Aim To compare the localization of lung adenocarcinoma with tumour size and lymphovascular invasion (LVI) presence, and to determine the frequency of metastasis findings in hilar and mediastinal lymph nodes depending on the localization of the tumour and status of lymphovascular invasion. Method This observational cross-sectional study included 261...

By Kemal Grbić, Bakir Mehić

Aim Wild mushroom intoxication is a public health problem, which causes a wide range of symptoms: from mild gastrointestinal symptoms to multiple organ failure and death. The present study aims to evaluate the epidemiology of mushroom intoxication in 4-year admissions of Razi Hospital, Qaemshahr, Mazandaran, Iran. MethodsMedical records of all iden...

By Iraj Goli Khatir, Seyed Mohammad Hosseininejad, Seyed Khosro Ghasempouri, Ailin Asadollahpoor, Siavash Moradi, Fatemeh Jahanian