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Original article

Pregnancy outcome after in vitro fertilization: a retrospective cohort study

By
Gordana Grgić ,
Gordana Grgić

Clinic for Gynecology and Obstetrics, University Clinical Center Tuzla , Tuzla , Bosnia and Herzegovina

Anis Cerovac Orcid logo ,
Anis Cerovac
Contact Anis Cerovac

Gyn and Obs, General Hospital Tešanj , Tešanj , Bosnia and Herzegovina

Azra Hadžimehmedović ,
Azra Hadžimehmedović

University Clinical Center Tuzla , Tuzla , Bosnia and Herzegovina

Selma Muratović ,
Selma Muratović

University Clinical Center Tuzla , Tuzla , Bosnia and Herzegovina

Asja Terzić ,
Asja Terzić

University Clinical Center Tuzla , Tuzla , Bosnia and Herzegovina

Ermin Čehić
Ermin Čehić

Cantonal Hospital Zenica , Zenica , Bosnia and Herzegovina

Editor: SELMA UZUNOVIĆ

Abstract

Aim To determine the outcome of pregnancies in women whose pregnancies resulted from in vitro fertilisatio  (IVF) procedure.

Methods This a retrospective cohort study was conducted at the Clinic for Gynecology and Obstetrics, University Clinical Center Tuzla, Bosnia and Herzegovina. Data from the delivery protocol were analyzed over a five-year period, from January 1, 2019, to December 31, 2023. A total of 257 deliveries from IVF pregnancies were analyzed, constituting the study group, while the control group consisted of an equal number of women with spontaneously conceived pregnancies. The following data were analyzed: baseline obstetrics  and neonatal characteristics, and presence of complications during pregnancy and delivery.

Results The average age of pregnant women was higher in the study compared to the control group (p=0.001). The average body weight and body length at birth were lower in the study group (p=0.001). The twin pregnancies were more frequent in the study group (p=0.0001). In the study group it was recorded largest number of primiparous women (p=0.0001). It was found higher number of newborns with Apgar scores <7 at the first and fifth minutes in the study group (p=0.0001). There were higher prevalence of preterm births and cesarean section in the study group (p=0.0001). Fetal asphyxia and breech presentation were more prevalent in the study group (p=0.008 and p<0.0001).

Consclusion Pregnancies resulting from IVF were still riskier than those resulting spontaneously.

Author Contributions

Conceptualization, G.G., A.C., A.H., S.M., A.T. and E.Č.; Data curation, G.G., A.C., S.M. and A.T.; Formal Analysis, G.G., A.H., S.M., A.T. and E.Č.; Investigation, G.G. and A.C.; Methodology, G.G. and A.C.; Supervision, G.G., A.C., A.H., S.M., A.T. and E.Č.; Writing – original draft, G.G. and A.C.; Writing – review & editing, G.G., A.C. and A.H. All authors have read and agreed to the published version of the manuscript.

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